Chapter 191: Going to the Countryside and Dilemma

Malaria is one of the oldest diseases of mankind.

In Wang Mengde's previous life, it was still an important public health issue that attracted widespread global attention and needed to be urgently addressed.

Not to mention in this era.

The disease is most serious in Southeast Asia and other places.

Southern China, especially Hainan Island and other areas, are hardest hit by malaria outbreaks.

Although for hundreds of years, countless people around the world have been searching for and researching ways and drugs to treat malaria.

It was also discovered that quinine, an effective ingredient for treating malaria, was isolated from cinchona bark, and quinine was artificially synthesized in the 1940s and 1950s.

Since then, scientists have continuously improved antimalarial drugs, forming various types of antimalarial drugs represented by quinine.

The successful development of various antimalarial drugs has greatly reduced the harm caused by malaria.

However, in the 1950s and 1960s, Plasmodium falciparum had already developed resistance to chloroquine in some areas.

To this end, major international research institutions or institutes are investing a lot of manpower and material resources to study malaria, with the main goal of finding new antimalarial drugs.

Due to the lack of funds and technology in China, there is currently no scientific research unit conducting research on malaria.

Wang Mengde has filled this gap.

After hearing about his research direction, President Lu and several vice presidents of the Institute of Traditional Chinese Medicine expressed their full support.

Whether it is human or material resources, as long as there is a need, you can apply unconditionally.

In terms of personnel, having these ten people as the main force is enough for the time being. Of course, during the research process, assistance from other institutes of the research institute will definitely be needed.

For example, when looking for antimalarial drugs from traditional Chinese medicine, the Institute of Traditional Chinese Medicine in the academy needs to help screen out some medicinal materials.

"Qian Dayong, take Zhu Tao, Sun Xiaoru, and Zhang Qiaoyu with you to the Institute of Traditional Chinese Medicine and ask Director Gu for help.

I consulted some traditional Chinese medicine literature, sorted and analyzed it, and listed the drugs and prescriptions that needed to be screened. ”

Wang Mengde said to Qian Dayong.

When there are other people around, he definitely can't call him Brother Dayong anymore.

Moreover, it was while I was at work.

As a leader, if you cannot distinguish between public and private affairs, it will be easy for those under you to disobey your orders.

"Yes, Director Wang."

Qian Dayong also understood and agreed loudly.

After saying that, he led the others to the Chinese Medicine Research Institute.

After they left, Wang Mengde looked at the remaining three people and continued, "Junior Brother Huang, Junior Brother Li, the three of you go to the laboratory and prepare the experimental materials in advance.

After they have screened out a batch of drug names, we will extract these drugs and prescriptions, mainly using two extraction methods: water decoction and ethanol.

By the way, after extraction, it will be sent for testing. Once a prescription or drug is found to be effective, animal experiments will be conducted.”

Thanks to our ancestors, the research on malaria has never stopped for thousands of years, and many prescriptions and research experiences have been left behind.

Although the effect may not be that good, it is definitely worth referring to for future generations.

"Yes, senior brother."

Huang Sizhong, Li Xiang and the other three said in unison.

They were all very excited and had great confidence in following their seniors in conducting research.

A while ago, the vaccine research team achieved remarkable results. Of course, apart from Huang Sizhong who participated in it and gained benefits, everyone else was extremely jealous.

This time, they were determined to cooperate with their seniors with more positive and practical actions to achieve success sooner.

After assigning the tasks and waiting for them all to leave, Wang Mengde sat on a chair, thinking in his mind.

With the successful experience of the previous life and his own medical skills, he plans to develop a prescription for treating malaria. It is estimated that it will be completed by the end of the year at the latest.

If good news can be received from the vaccine research team as well, it would be double happiness.

Thinking of this, he stood up confidently and walked towards Pu Lao's office, ready to tell his teacher the good news in advance.

When we arrived at the place, we saw Mr. Pu wearing a pair of reading glasses and reading a medical book attentively.

"gentlemen."

"Meng De is here."

Pu Lao heard the voice, raised his head, put the medical book on the table, and said cheerfully: "There is a new pack of tea leaves in the drawer, you can make it yourself."

Wang Mengde was not polite and took out the tea leaves as if he knew the trick.

"Wow, sir, this is Pu'er! I must try it."

As he spoke, he first filled Pu Lao's teacup with hot water, then picked up another clean cup and carefully made himself a cup of Pu'er tea.

"Haha, this is an old friend of mine from Yunnan Province. His disciple came to Beijing for work and happened to bring me two packs. If you like it, take one pack back and drink it."

Master Pu knew that his favorite disciple liked to drink tea, so he waved his hand and said.

He now treats Wang Mengde much better than his own son.

Whenever there was anything good, he would be given the first chance. This caused Senior Brother Zhixiao to often express jealously, "This son of mine must have been adopted."

Otherwise, why would they rather leave good things like cigarettes, alcohol and tea at home and not let him take them?

But as long as Wang Mengde asked, even without him asking directly, his father would take the initiative to give these to him.

This made him feel very upset.

Of course, he was just jealous. He also liked this junior brother very much.

Last time, he participated in the compilation of the "Barefoot Doctor Manual", which benefited him a lot. At the end of last year, relying on this resume, he was rated as an advanced person in the hospital and was promoted to a higher level.

"Teacher, I'm not used to drinking Pu'er, I just try it occasionally, I don't want this."

Wang Mengde refused.

He still prefers to drink green tea more.

"Well, OK, then I'll ask for a few ounces of tea when I go to see the leader later."

Pu Lao knew his character and did not force him, so he promised again.

However, this time, he did not say that he wanted a kilogram of tea, mainly because the supply of tea is even tighter now.

Even if the vouchers were supplied, all the tea on the market was out of stock.

Taking into account the "political impact", in order to fill the market gap in the capital, the state had to recover a small part from the inventory of major government agencies, guest houses, hotels and other units.

According to statistics, hundreds of quintals of tea were recovered each year, which slightly eased the financial tension in the capital.

But other places don't have this treatment. Most people can hardly see a handful of tea in a year.

Therefore, the few taels he could get was already his limit.

"Thank you, sir."

Wang Mengde said happily.

He and Wang Hao both like to drink tea, but only during the Mid-Autumn Festival and National Day can they get a voucher to supply one or two taels of tea.

This amount is only enough for two people to drink for a few days.

Now that he has the few taels of liquor sent by Old Pu, he can buy some more from the space, so he won’t have to save on drinking later.

The two chatted casually for a few more words, and then Wang Mengde got to the point. He talked about his thoughts on malaria in detail.

Pu Lao listened quietly. After he finished speaking, he was silent for a while before slowly speaking:
"Meng De, I've thought about it. What you just said is very comprehensive. There is nothing else to add in terms of medical skills.

I will give you a message that I hope will be helpful to you. If you encounter any problems during the research process, don’t rush into it. Take your time. Maybe there will be a turning point.”

"Yes, sir, I remember that."

Wang Mengde said solemnly.

Thereafter.

For about a month, everyone, including him, was busy. After Huang Sizhong and Li Xiang prepared the experimental equipment, they also joined Qian Dayong's team. In their free time, they went to the Institute of Traditional Chinese Medicine to look through ancient books and related documents.

In those days, there were no computers for searching, and people had to rely entirely on flipping through the vast amount of books, one book at a time, one page at a time.

Fortunately, Director Gu of the Chinese Medicine Research Institute also knew what was important and he mobilized many employees in the institute to help with the search.

Until the day before National Day, only a little more than half of the ancient books and documents in the institute had been searched through.

"Brother, let's work overtime during the National Day holiday to find someone."

In the office, Zhang Qiaoyu suggested softly with big bags under her eyes.

Several other people also echoed.

"Haha, don't worry, this is not something that can be done overnight. Let's take a good rest. When we are back from vacation and holidays and have more energy, it won't be too late to look for it later."

Wang Mengde smiled and comforted him.

He didn't expect that the screening stage would be so difficult.

It is a big project to find some useful information from so many books.

However, I kept Pu Lao's teachings in mind and was not too anxious.

"Brother, we have five days off this time, which is too long. How about we take two days off, and for the remaining three days, everyone should come and work overtime."

At this time, Huang Sizhong stood behind several people and spoke.

This year's National Day is still a three-day holiday, and the middle day happens to be a Sunday, so according to national holiday regulations, it is extended by one day.

This just happens to be connected with the Mid-Autumn Festival.

So, there were five consecutive days of holidays.

Last month, Wang Mengde applied for 20 kilograms of cornmeal for each of them. With this food every month, their complexion finally improved a lot.

At the same time, it also makes them very motivated and they always think about working overtime.

“There is no need to work overtime for the time being, and the screening work will be completed in about a month.

We have more important tasks to do later, and you will have to work overtime, so now you should all rest more and conserve your energy."

Wang Mengde said with a smile.

After hearing what their senior brother said, several people returned in disappointment.

After work in the evening, I returned home.

At the dinner table, He Shengnan asked quietly, "Meng De, you don't have to participate in some activities during this year's National Day, right?"

Last year’s National Day was our tenth anniversary, so it was a big celebration.

On that day, Wang Mengde was also invited to attend the ceremony.

The remaining two days were also occupied by various other activities.

“I’m not going anywhere this year. I’m just staying at home.”

Wang Mengde said with a smile.

He turned down invitations from several units, including one that was hosted by the city of Beijing.

In order to make good use of a few days to spend time with his family, he had a feeling that after the holidays, he might not have much free time.

"Really? That's great."

Before He Shengnan could speak, Wang Yuanchao and Wang Weiguo started shouting excitedly.

"Brother, you have to play with us these days."

Even Wang Yuanxun and Wang Yuandi were grinning with joy. Although Yaya didn't know the details, she also started giggling.

"Okay, I'll play with you guys these few days."

Wang Mengde smiled and said, "Let's go to the movies first, then go to Wangfujing, and then buy mooncakes and rabbit statues."

He had planned all this in advance, so he just said it out loud.

"Meng De, when you take them to buy mooncakes, remember to bring both supplementary food books. Our family can buy four in total."

Ran Xiaomei saw the children so happy and gave them instructions with a smile.

In the past, when her son just got married and wanted to separate from the family, she didn’t quite understand it at the time.

After the ticket policy was gradually implemented in recent years, she felt that her son was really far-sighted.

Now that we have split up, the quantity of many things is doubled.

If the family had not divided up, they would have only had one copy.

"Mom, I get it. By the way, I have other channels to buy mooncakes. I can buy a dozen more."

Wang Mengde agreed and then revealed another piece of news.

This channel is in his space.

This year the quota is only four mooncakes, but there are nine people in their family, so one mooncake is not enough for two people on average.

After all, it is a very important annual festival, so he plans to buy more from his space.

"Can I buy a dozen more? That's great."

Ran Xiaomei said excitedly: "When the time comes, give four pieces to my in-laws."

There are exactly six people in the He family, including Grandpa He. They can buy two pieces at a fixed rate. They will send four more pieces over, which is just enough for each person to get one piece.

No one was surprised by his energy. After all, many of the supplies in the house were brought back by him from outside.

Especially eggs, the supply has been out of stock this year, but he can still bring back dozens of them every once in a while.

Fresh meat that other people couldn’t buy, every time he used the meat coupons, he could buy the best and fresh pork belly.

"Okay, I'll send it over the day before Mid-Autumn Festival, and I'll send some other things too."

Wang Mengde nodded.

This time, He Shengnan did not object.

She also knew that her mother-in-law sincerely wanted to give the gift to her parents' home, and she also knew the difficulties her parents' home faced.

She remembers all the good things about her husband's family.

at night.

When both of them were exhausted and ready to go to bed, He Shengnan suddenly whispered, "Meng De, let's take a day off and take the kids to visit grandpa and grandma in the countryside."

Just now at the dinner table, the family had discussed that Wang Hao and Wang Mengde would take a day off to visit the elderly in the countryside.

Now seeing her suddenly asking to go to the countryside together, Wang Mengde asked curiously: "What's wrong? Why do you want to go together?"

"It's okay. I just want to visit my grandparents and take the kids to the countryside for a walk."

He Shengnan hugged his arm and spoke softly.

"Okay, then take a few children with you and let them see the sufferings in the countryside."

This time the holiday.

For Wang Yuanchao and Wang Weiguo, it was a baptism.

After the trip to the countryside, they came back obviously more mature and stable.

After the holiday, just as Wang Mengde expected, they became increasingly busy.

At the end of October, they finally completed the initial screening task.

After sorting and analysis, the key drugs screened were: Aconitum, Prunus mume, Turtle shell, Artemisia annua, etc., and nearly a hundred prescriptions were also screened.

By extracting with water or ethanol, they sent a total of 10 batches of 173 samples to the Academy of Military Medical Sciences for testing in a short period of time.

However, the results of the test feedback disappointed Wang Mengde.

Their research ran into trouble.

(End of this chapter)